Common genetic variation drives molecular heterogeneity in human iPSCs

Cellular phenotyping of 28 human induced pluripotent stem cell lines from 14 donors within the framework of the HipSci project. Cells are plated sparsely, 3000 per 96 well for 24 hours on wells coated with three diverse concentrations of Fibronectin. Note the images relating to the publication 'Common genetic variation drives molecular heterogeneity in human iPSCs' were released in May 2017. Version History In February 2019, this screen was extended and 87 human induced pluripotent stem cell lines from 62 donors were added. All data from this study is included in idr0037-vigilante-hipsci.

Kilpinen H, Goncalves A, Leha A, Afzal V, Alasoo K, Ashford S, Bala S, Bensaddek D, Casale FP, Culley OJ, Danecek P, Faulconbridge A, Harrison PW, Kathuria A, McCarthy D, McCarthy SA, Meleckyte R, Memari Y, Moens N, Soares F, Mann A, Streeter I, Agu CA, Alderton A, Nelson R, Harper S, Patel M, White A, Patel SR, Clarke L, Halai R, Kirton CM, Kolb-Kokocinski A, Beales P, Birney E, Danovi D, Lamond AI, Ouwehand WH, Vallier L, Watt FM, Durbin R, Stegle O, Gaffney DJ

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