Protein Kinase C and the stress response pathways are required for kinetochore homeostasis.
In this screen, Synthetic Genetic Array (SGA) methodology (Tong et al, 2001) was used to combine the DAD4-YFP and SPC42-RFP alleles with the non-essential deletion collection (Winzeler et al, 1999), which includes 4746 separate viable deletion strains, to systematically assess the effect of specific mutations on the kinetochore.
Ledesma-Fernández E, Herrero E, Ólafsson G, Thorpe PH
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idr0011-ledesmafernandez-dad4/screenA ()
idr0011-ledesmafernandez-dad4/screenB ()
idr0011-ledesmafernandez-dad4/screenC ()
idr0011-ledesmafernandez-dad4/screenD ()
idr0011-ledesmafernandez-dad4/screenE ()
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screenA ( , parquet: )
screenB ( , parquet: )
screenC ( , parquet: )
screenD ( , parquet: )
screenE ( , parquet: )
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Sample Type: cell
Organism: Saccharomyces cerevisiae
Study Type: high content screen
Screen Type: primary screen
Screen Technology Type: gene deletion screen
Imaging Method: fluorescence microscopy
Copyright: Ledesma-Fernandez et al
Annotation File: idr0011-screenA-annotation.csv
